It is very important that your doctor check your progress at regular visits to make sure that ACIPHEX is working properly and to check for unwanted effects. If your condition does not improve, or it it becomes worse, discuss this with your doctor.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Rare
  • Breathing interruptions;  bloody urine ;  convulsions (seizures);  chills, fever, or sore throat;  continuing ulcers or sores in mouth;  unusual bleeding or bruising;  unusual tiredness or weakness;  yellow eyes or skin 
  
  

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

• More common
  • Headache 
  
  

• Less common or rare
  • Constipation;  diarrhea ;  dizziness;  feeling weak;  gas;  heartburn;  itchy skin;  nausea and vomiting;  numbness, tingling, pain, or weakness in hands or feet;  sleepiness;  stomach pain 
  
  

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.